Cryptic crossword clue
Starts to undertake the experiment, replacing internal organs 5

The most common and most likely answer to this crossword clue is the 5 letter word UTERI

I've seen this crossword clue in The Times
U
T
E
R
I


Buddy explains!

The straight part
We know that "organs" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case organs = uteri.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does UTERI mean?

UTERI noun
  1. The womb, an organ of the female reproductive system in which the young are conceived and develop until birth.

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