Cryptic crossword clue
State of equilibrium is upset, so son falls in river 8

The most common and most likely answer to this crossword clue is the 8 letter word ISOSTASY

I've seen this crossword clue in Financial Times
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Buddy explains!

The straight part
We know that "State of equilibrium" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case state of equilibrium = isostasy.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does ISOSTASY mean?

ISOSTASY noun
  1. The state of balance or pressure equilibrium thought to exist within the Earth's crust, whereby the upper lithosphere floats on denser magma beneath.

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