Cryptic crossword clue
State of sexual arousal certainly returned around second peak of testosterone 6

The most common and most likely answer to this crossword clue is the 6 letter word ESTRUS

E
S
T
R
U
S

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The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does ESTRUS mean?

ESTRUS noun
  1. A biting fly of the genus Oestrus; a botfly.
  2. A bite or sting.
  3. A passion or frenzy.
  4. A female animal's readiness to mate; heat, rut.

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