Cryptic crossword clue
Sterilises ruined cities and finds one is lost 10

The most common and most likely answer to this crossword clue is the 10 letter word DISINFECTS

I've seen this crossword clue in The Daily Telegraph
D
I
S
I
N
F
E
C
T
S

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The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does DISINFECTS mean?

DISINFECTS verb
  1. To sterilize by the use of cleaning agent.

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