Cryptic crossword clue
Sticker if used inside city limits: “Reduce presence of calcium” 9

The most common and most likely answer to this crossword clue is the 9 letter word DECALCIFY

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Buddy explains!

The straight part
We know that "Reduce presence of calcium" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case reduce presence of calcium = decalcify.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does DECALCIFY mean?

DECALCIFY verb
  1. To deprive of calcareous matter.

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