The most common and most likely answer to this crossword clue is the 9 letter word AQUITAINE
I've seen this crossword clue in Financial Times
A
Q
U
I
T
A
I
N
E
More clues leading to the result AQUITAINE
- Motorists about to leave home finally choose somewhere in France
- Stop among motoring group in English region of France
- Academician fairly retaining own Scottish duchy
- A senior getting abandoned inside Eleanor’s home?
- A broken antique, I found inside an old region of France
- A home in a somewhat historical region of France
Buddy explains!

The straight part
We know that "region of France" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case region of france = aquitaine.The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.