The most common and most likely answer to this crossword clue is the 8 letter word AFFLICTS
A
F
F
L
I
C
T
S
Buddy explains!
The straight part
We know that "Strains" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case strains = afflicts.The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.
What does AFFLICTS mean?
AFFLICTS verb- To cause (someone) pain, suffering or distress.
- To strike or cast down; to overthrow.
- To make low or humble.