The most common and most likely answer to this crossword clue is the 6 letter word OEUVRE
I've seen this crossword clue in Financial Times
O
E
U
V
R
E
More clues leading to the result OEUVRE
- Skilfully negotiate – without leading man getting work
- Guide without staff or work
- ‘Work over, beat up’: boxing spelt out essentially
- Work as engineer, not leading man
- Edges of one rectangle framing a sort of light work
- Stratagem to conceal staff work
- Work & Love revue production
- One’s emptied volume into river, the entire works
- Work and overwork for European Union entry
- Work on extension, usually very reliable, erratic initially
Buddy explains!

The straight part
We know that "work" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case work = oeuvre.The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.
What does OEUVRE mean?
OEUVRE noun- A work of art.
- The complete body of an artist's work.