Cryptic crossword clue
Stray rats in the Indian restaurant; basically they are a nuisance 9

The most common and most likely answer to this crossword clue is the 9 letter word IRRITANTS

I
R
R
I
T
A
N
T
S

Buddy explains!

The straight part
We know that "they are a nuisance" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case they are a nuisance = irritants.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does IRRITANTS mean?

IRRITANTS noun
  1. Any medication designed to cause irritation
  2. A source of irritation.

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