The most common and most likely answer to this crossword clue is the 5 letter word WRIST
I've seen this crossword clue in The Times
W
R
I
S
T
Buddy explains!

The straight part
We know that "Stroke" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case stroke = wrist.The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.
What does WRIST mean?
WRIST noun- The complex joint between forearm bones, carpus, and metacarpals where the hand is attached to the arm; the carpus in a narrow sense.
- A stud or pin which forms a journal.
- To hit a wrist shot