Cryptic crossword clue
Strong and sour etc after modifying sweet stuff 8

The most common and most likely answer to this crossword clue is the 8 letter word FRUCTOSE

I've seen this crossword clue in Independent
F
R
U
C
T
O
S
E

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The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
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What does FRUCTOSE mean?

FRUCTOSE noun
  1. A monosaccharide ketose sugar, formula C6H12O6.

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