Cryptic crossword clue
Struggles of the northbound prophet going around South Carolina to get satin stitched 11

The most common and most likely answer to this crossword clue is the 11 letter word RESISTANCES

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Buddy explains!

The straight part
We know that "Struggles" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case struggles = resistances.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does RESISTANCES mean?

RESISTANCES noun
  1. The act of resisting, or the capacity to resist.
  2. A force that tends to oppose motion.
  3. Electrical resistance.
  4. An underground organisation engaged in a struggle for liberation from forceful occupation; a resistance movement.

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