Cryptic crossword clue
Study subject in school that gives moral guidance 10

The most common and most likely answer to this crossword clue is the 10 letter word CONSCIENCE

I've seen this crossword clue in The Sunday Telegraph
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Buddy explains!

The straight part
We know that "that gives moral guidance" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case that gives moral guidance = conscience.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does CONSCIENCE mean?

CONSCIENCE noun
  1. The moral sense of right and wrong, chiefly as it affects one's own behaviour.
  2. (chiefly fiction) A personification of the moral sense of right and wrong, usually in the form of a person, a being or merely a voice that gives moral lessons and advices.
  3. Consciousness; thinking; awareness, especially self-awareness.

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