Cryptic crossword clue
Stupefies fellow doctors after uncertainty at the outset 7

The most common and most likely answer to this crossword clue is the 7 letter word BENUMBS

I've seen this crossword clue in Financial Times
B
E
N
U
M
B
S

Buddy explains!

The straight part
We know that "Stupefies" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case stupefies = benumbs.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does BENUMBS mean?

BENUMBS verb
  1. To make numb, as by cold or anesthetic.
  2. To deaden, dull (the mind, faculties, etc.).

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