The most common and most likely answer to this crossword clue is the 13 letter word DISADVANTAGED
I've seen this crossword clue in The Times
D
I
S
A
D
V
A
N
T
A
G
E
D
Buddy explains!
The straight part
We know that "Such people have little in common" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case such people have little in common = disadvantaged.The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.
What does DISADVANTAGED mean?
DISADVANTAGED verb- To place at a disadvantage.
- Lacking an advantage relative to another.
- Poor; in financial difficulties.