The most common and most likely answer to this crossword clue is the 8 letter word CAYENNE:
I've seen this crossword clue in The Guardian
C
A
Y
E
N
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:
Buddy explains!
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.
What does CAYENNE: mean?
CAYENNE: noun- Cayenne pepper.