Cryptic crossword clue
Suppressing any reported horse tranquilliser for peace of mind 11

The most common and most likely answer to this crossword clue is the 11 letter word EQUILIBRIUM

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Buddy explains!

The straight part
We know that "peace of mind" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case peace of mind = equilibrium.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does EQUILIBRIUM mean?

EQUILIBRIUM noun
  1. The condition of a system in which competing influences are balanced, resulting in no net change.
  2. Mental balance.
  3. The state of a reaction in which the rates of the forward and reverse reactions are the same.
  4. The state of a body at rest or in uniform motion in which the resultant of all forces on it is zero.

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