Cryptic crossword clue
Surgery primarily considered after drug is rejected 8

The most common and most likely answer to this crossword clue is the 8 letter word ESCHEWED

E
S
C
H
E
W
E
D


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The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does ESCHEWED mean?

ESCHEWED verb
  1. To avoid; to shun, to shy away from.

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