The most common and most likely answer to this crossword clue is the 6 letter word BIOPSY
I've seen this crossword clue in The Guardian
B
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More clues leading to the result BIOPSY
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The cryptic/wordplay part
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What does BIOPSY mean?
BIOPSY noun- The removal and examination of a sample of tissue, cells, or bodily fluid from a living body for diagnostic purposes.
- To take a sample (a biopsy) for pathological examination.