The most common and most likely answer to this crossword clue is the 11 letter word GHOSTBUSTER
I've seen this crossword clue in The Times
G
H
O
S
T
B
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R
More clues leading to the result GHOSTBUSTER
Buddy explains!
The straight part
We know that "hunter of some spirit" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case hunter of some spirit = ghostbuster.The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.
What does GHOSTBUSTER mean?
GHOSTBUSTER noun- Someone who purports to rid a place of ghosts.