Cryptic crossword clue
Sweet mouse ill with flu in need of treatment 11

The most common and most likely answer to this crossword clue is the 11 letter word MELLIFLUOUS

I've seen this crossword clue in Independent
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Buddy explains!

The straight part
We know that "Sweet" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case sweet = mellifluous.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does MELLIFLUOUS mean?

MELLIFLUOUS adjective
  1. Flowing like honey.
  2. Sweet, smooth and musical; pleasant to hear (generally used of a person's voice, tone or writing style).

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