Cryptic crossword clue
Switching second and fifth would create the opposite, see 7

The most common and most likely answer to this crossword clue is the 7 letter word OBSERVE

O
B
S
E
R
V
E


Buddy explains!

The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does OBSERVE mean?

OBSERVE verb
  1. To notice or view, especially carefully or with attention to detail.
  2. To follow or obey the custom, practice, or rules (especially of a religion).
  3. To take note of and celebrate (a holiday or similar occurrence).
  4. To comment on something; to make an observation.

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