Cryptic crossword clue
Table water in Yorkshire returned sample of bacterium 8

The most common and most likely answer to this crossword clue is the 8 letter word LISTERIA

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Buddy explains!

The straight part
We know that "sample of bacterium" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case sample of bacterium = listeria.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does LISTERIA mean?

LISTERIA noun
  1. Any rod-shaped, gram-positive bacterium, of the genus Listeria, especially those responsible for the bacterial infection listeriosis.

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