Cryptic crossword clue
Tablet with primrose that’s got rid of cold — you’ll sleep on it 10

The most common and most likely answer to this crossword clue is the 10 letter word PILLOWSLIP

I've seen this crossword clue in The Daily Telegraph
P
I
L
L
O
W
S
L
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P

Buddy explains!

The straight part
We know that "you’ll sleep on it" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case you’ll sleep on it = pillowslip.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does PILLOWSLIP mean?

PILLOWSLIP noun
  1. A pillow case.

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