Cryptic crossword clue
Tablets, we hear, providing comfort 4

The most common and most likely answer to this crossword clue is the 4 letter word EASE

I've seen this crossword clue in The Guardian
E
A
S
E


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The straight part
We know that "comfort" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case comfort = ease.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does EASE mean?

EASE noun
  1. Ability, the means to do something, particularly:
  2. Comfort, a state or quality lacking unpleasantness, particularly:
  3. Relief, an end to discomfort, particularly:
  4. A convenience; a luxury.
  5. A relief; an easement.
EASE verb
  1. To free (something) from pain, worry, agitation, etc.
  2. To alleviate, assuage or lessen (pain).
  3. To give respite to (someone).
  4. To loosen or slacken the tension on a line.
  5. To reduce the difficulty of (something).
  6. To move (something) slowly and carefully.
  7. To lessen in severity.
  8. To proceed with little effort.

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