The most common and most likely answer to this crossword clue is the 4 plus 2 letter word LOOK TO
L
O
O
K
T
O
More clues leading to the result LOOK TO
Buddy explains!
The straight part
We know that "Take care of" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case take care of = look to.The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.