Cryptic crossword clue
Take courage from sniper eliminating Guam's leader 5

The most common and most likely answer to this crossword clue is the 5 letter word UNMAN

I've seen this crossword clue in The Times
U
N
M
A
N

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The straight part
We know that "Take courage from" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case take courage from = unman.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does UNMAN mean?

UNMAN verb
  1. To castrate; to remove the manhood of.
  2. To sap (a person) of the strength, whether physical or emotional, required to deal with a situation.
  3. To deprive of men.

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