The most common and most likely answer to this crossword clue is the 6 letter word GRUDGE
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Buddy explains!

The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.
What does GRUDGE mean?
GRUDGE noun- Deep-seated and/or long-term animosity or ill will about something or someone, especially due to a past misdeed or mistreatment.
- To be unwilling to give or allow (someone something).
- To grumble, complain; to be dissatisfied.
- To hold or harbour with malicious disposition or purpose; to cherish enviously.
- To feel compunction or grief.