The most common and most likely answer to this crossword clue is the 5 letter word ADOPT
I've seen this crossword clue in The Guardian
A
D
O
P
T
More clues leading to the result ADOPT
- Take up difficulty over point
- Take notice? No point
- Take on a party post, though not having the heart
- Take on appropriate accommodation for party
- Take in party with suitable clothing
- Take trouble with exercise
- Embrace and fuss, then part
- Introduce to family occasion, given suitable clothing
- Put on fitting clothing for function
- Take over training with fuss at the front
Buddy explains!

The straight part
We know that "Take on" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case take on = adopt.The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.
What does ADOPT mean?
ADOPT verb- To take by choice into relationship (a child, heir, friend, citizen, etc.)
- To take or receive as one's own what is not so naturally.
- To select and take or approve.
- To win ten consecutive games against an opponent