Cryptic crossword clue
Taking advantage, 22 poison, unfortunately 11

The most common and most likely answer to this crossword clue is the 11 letter word OPPORTUNISM

I've seen this crossword clue in Independent
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Buddy explains!

The straight part
We know that "Taking advantage" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case taking advantage = opportunism.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does OPPORTUNISM mean?

OPPORTUNISM noun
  1. The practice of taking advantage of any situations or people to achieve an end, often with no regard for principles or consequences.

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