Cryptic crossword clue
Talk spitefully about side with incisiveness 8

The most common and most likely answer to this crossword clue is the 8 letter word BACKBITE

I've seen this crossword clue in The Times
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The straight part
We know that "Talk spitefully about" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case talk spitefully about = backbite.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does BACKBITE mean?

BACKBITE noun
  1. One who engages in backbiting; a backbiter.
BACKBITE verb
  1. To make spiteful slanderous or defamatory statements about someone.
  2. To attack from behind or when out of earshot with spiteful or defamatory remarks.
  3. To speak badly of an absent individual.

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