Cryptic crossword clue
Talks a lot with holy men going east and west 7

The most common and most likely answer to this crossword clue is the 7 letter word RABBITS

I've seen this crossword clue in The Daily Telegraph
R
A
B
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Buddy explains!

The straight part
We know that "Talks a lot" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case talks a lot = rabbits.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does RABBITS mean?

RABBITS noun
  1. A mammal of the family Leporidae, with long ears, long hind legs and a short, fluffy tail.
  2. The meat from this animal.
  3. The fur of a rabbit typically used to imitate another animal's fur.
  4. A runner in a distance race whose goal is mainly to set the pace, either to tire a specific rival so that a teammate can win or to help another break a record; a pacesetter.
  5. A very poor batsman; selected as a bowler or wicket-keeper.
  6. A large element at the beginning of a list of items to be bubble sorted, and thus tending to be quickly swapped into its correct position. Compare turtle.
  7. Rarebit; Welsh rabbit or a similar dish: melted cheese served atop toast.

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