The most common and most likely answer to this crossword clue is the 5 letter word ENEMA
I've seen this crossword clue in The Guardian
E
N
E
M
A
More clues leading to the result ENEMA
- Medical procedure possibly reduced lameness on reflection
- Servants in attendance extremely upset, as behind procedure?
- Workers in A&E reversed invasive procedure
- . Obscene magazine shows medical procedure
- Some upstanding militiamen ended purge
- Tame! Newcastle after setback having big clear-out
- … mean the end of one nasty medical procedure
- Purgative wrapped inside polythene material
- People in A&E returned to get liquid injected
- Evacuation from east? So be it: to the west
Buddy explains!
The straight part
We know that "big clear-out" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case big clear-out = enema.The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.
What does ENEMA mean?
ENEMA noun- An injection of fluid into the large intestine by way of the rectum, usually for medical purposes.
- The fluid so injected.
- A device for administering such an injection.