Cryptic crossword clue
Teetotalism met setback – peer can get fuddled 10

The most common and most likely answer to this crossword clue is the 10 letter word TEMPERANCE

I've seen this crossword clue in Financial Times
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Buddy explains!

The straight part
We know that "Teetotalism" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case teetotalism = temperance.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does TEMPERANCE mean?

TEMPERANCE noun
  1. Habitual moderation in regard to the indulgence of the natural appetites and passions; restrained or moderate indulgence
  2. Moderation, and sometimes abstinence, in respect to using intoxicating liquors.
  3. Moderation of passion
  4. State with regard to heat or cold; temperature.

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