Cryptic crossword clue
Tenant clutching bottle’s last to come in again 2-5

The most common and most likely answer to this crossword clue is the 8 letter word RE-ENTER

I've seen this crossword clue in The Guardian
R
E
-
E
N
T
E
R


Buddy explains!

The straight part
We know that "come in again" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case come in again = re-enter.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does RE-ENTER mean?

RE-ENTER verb
  1. To enter again; return into.
  2. To enter again; retype, reinput.
  3. (engraving) To cut deeper where the aqua fortis has not bitten sufficiently.

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