The most common and most likely answer to this crossword clue is the 13 letter word THICK-SKINNED
I've seen this crossword clue in Financial Times
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More clues leading to the result THICK-SKINNED
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The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.
What does THICK-SKINNED mean?
THICK-SKINNED adjective- Having a thick skin.
- Not easily offended.
- Insensitive to the feelings of others; callous.