Cryptic crossword clue
Test substance of date shown in lease 7

The most common and most likely answer to this crossword clue is the 7 letter word REAGENT

I've seen this crossword clue in The Times
R
E
A
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T


Buddy explains!

The straight part
We know that "Test substance" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case test substance = reagent.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does REAGENT mean?

REAGENT noun
  1. A compound or mixture of compounds used to treat or test materials, samples, other compounds or reactants in a laboratory or sometimes an industrial setting.

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