Cryptic crossword clue
The 25 are on these drugs

The most common and most likely answer to this crossword clue is the 6 letter word UPPERS

I've seen this crossword clue in Independent
U
P
P
E
R
S

Buddy explains!

The straight part
We know that "drugs" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case drugs = uppers.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does UPPERS mean?

UPPERS noun
  1. A stimulant, such as amphetamine, that increases energy and decreases appetite.
  2. The upper portion of something
  3. Someone with higher social standing
  4. That which is higher, contrasted with the lower.
  5. A spiritual passageway through which consciousness can reach a higher dimension.

Latest crossword clues with full explanations