Cryptic crossword clue
The blues tunes — millions I’d played 15

The most common and most likely answer to this crossword clue is the 15 letter word DISILLUSIONMENT

I've seen this crossword clue in The Daily Telegraph
D
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Buddy explains!

The straight part
We know that "The blues" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case the blues = disillusionment.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does DISILLUSIONMENT mean?

DISILLUSIONMENT noun
  1. A feeling of disappointment, akin to depression, arising from the realization that something is not what it was expected or believed to be, possibly accompanied by philosophical angst from having one's beliefs challenged.
  2. The act of freeing from an illusion; the state of being freed therefrom.

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