The most common and most likely answer to this crossword clue is the 7 letter word HEADERS
H
E
A
D
E
R
S
Buddy explains!
The straight part
We know that "initial letters" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case initial letters = headers.The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.
What does HEADERS mean?
HEADERS noun- The upper portion of a page (or other) layout.
- Text, or other visual information, used to mark off a quantity of text, often titling or summarizing it.
- Text, or other visual information, that goes at the top of a column of information in a table.
- A font, text style, or typesetting used for any of the above.
- The first part of a file or record that describes its contents.
- The first part of a packet or stream, often containing its address and descriptors.
- A brick that is laid sideways at the top of a wall or within the brickwork with the short side showing.
- A horizontal structural or finish piece over an opening.
- A machine that separates and gathers the heads of grain etc.
- The act of hitting the ball with the head.
- Someone who heads the ball.
- A headlong fall or jump.
- A raised tank that supplies water at constant pressure, especially to a central heating and hot water system.
- A pipe which connects several smaller pipes.
- The rodeo performer who drives the steer toward the heeler to be tied.
- One who puts a head on something.
- A file, usually in the form of source code, that is automatically included in another source file by the compiler.
- A file that contains declarations but no implementations.