Cryptic crossword clue
The nerve of Rockefeller Center housing a political group, extremely reactionary 10

The most common and most likely answer to this crossword clue is the 10 letter word EFFRONTERY

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Buddy explains!

The straight part
We know that "The nerve" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case the nerve = effrontery.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does EFFRONTERY mean?

EFFRONTERY noun
  1. Insolent and shameless audacity.
  2. An act of insolent and shameless audacity.

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