Cryptic crossword clue
The old begin as fools, entering college 6

The most common and most likely answer to this crossword clue is the 6 letter word INCEPT

I
N
C
E
P
T

Buddy explains!

The straight part
We know that "The old begin" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case the old begin = incept.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does INCEPT mean?

INCEPT verb
  1. To take in or ingest.
  2. To begin.
  3. To begin a Master of Arts degree at a university.

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