Cryptic crossword clue
The old street accommodates a brewery agent 5

The most common and most likely answer to this crossword clue is the 5 letter word YEAST

Y
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A
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Buddy explains!

The straight part
We know that "brewery agent" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case brewery agent = yeast.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does YEAST mean?

YEAST noun
  1. An often humid, yellowish froth produced by fermenting malt worts, and used to brew beer, leaven bread, and also used in certain medicines.
  2. A single-celled fungus of a wide variety of taxonomic families.
  3. A frothy foam.
YEAST verb
  1. To ferment.
  2. (of something prepared with a yeasted dough) To rise.
  3. To exaggerate

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