Cryptic crossword clue
The Queen spoken to, having squashed rat that’s driven over

The most common and most likely answer to this crossword clue is the 7 letter word MACADAM

I've seen this crossword clue in The Guardian
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Buddy explains!

The straight part
We know that "that’s driven over" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case that’s driven over = macadam.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does MACADAM mean?

MACADAM noun
  1. The surface of a road consisting of layers of crushed stone (usually tar-coated for modern traffic).
  2. Any road or street.
MACADAM verb
  1. To cover or surface with macadam.

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