Cryptic crossword clue
The sixth sense is related to wine 6

The most common and most likely answer to this crossword clue is the 6 letter word VINOUS

I've seen this crossword clue in Independent
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Buddy explains!

The straight part
We know that "related to wine" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case related to wine = vinous.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does VINOUS mean?

VINOUS adjective
  1. Pertaining to or having the characteristics of wine.
  2. Tending to drink wine excessively.
  3. Affected by the drinking of wine.

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