Cryptic crossword clue
Their mum’s suffering with a painful condition 10

The most common and most likely answer to this crossword clue is the 10 letter word RHEUMATISM

I've seen this crossword clue in The Times
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The straight part
We know that "painful condition" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case painful condition = rheumatism.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does RHEUMATISM mean?

RHEUMATISM noun
  1. Any disorder of the muscles, tendons, joints, bones, nerves, characterized by pain, discomfort and disability.
  2. Atrophic arthritis, rheumatoid arthritis

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