Cryptic crossword clue
They attack with wild Alsatians with safety first 10

The most common and most likely answer to this crossword clue is the 10 letter word ASSAILANTS

I've seen this crossword clue in The Daily Telegraph
A
S
S
A
I
L
A
N
T
S

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The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does ASSAILANTS mean?

ASSAILANTS noun
  1. Someone who attacks or assails another violently, or criminally.
  2. (by extension) A hostile critic or opponent.

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