Cryptic crossword clue
They colour red say, losing heart when embarrassed

The most common and most likely answer to this crossword clue is the 5 letter word DYERS

I've seen this crossword clue in Independent
D
Y
E
R
S

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The straight part
We know that "They colour" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case they colour = dyers.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does DYERS mean?

DYERS noun
  1. One who dyes, especially one who dyes cloth etc. as an occupation.

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