Cryptic crossword clue
Think Dennis gets upset, being this, perhaps 4-7

The most common and most likely answer to this crossword clue is the 12 letter word THIN-SKINNED

I've seen this crossword clue in The Times
T
H
I
N
-
S
K
I
N
N
E
D


Buddy explains!

The straight part
We know that "upset, being this, perhaps" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case upset, being this, perhaps = thin-skinned.
The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.
This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.

What does THIN-SKINNED mean?

THIN-SKINNED adjective
  1. Overly sensitive to criticism; quick to take offence; irritable; touchy

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