The most common and most likely answer to this crossword clue is the 10 letter word RUMINATION
I've seen this crossword clue in The Times
R
U
M
I
N
A
T
I
O
N
More clues leading to the result RUMINATION
- Deep thought: odd state to beset one
- Thinking of strange island state
- Thinking of motorway in disrepair
- During fall, man’s first thought
- To interrupt collapse, a minute’s thought
- Musing, Mark stops downfall
- Maiden in state of collapse thinking
- Persian poet gathers people for an act of meditation
- Thinking downfall bites him in the rear
Buddy explains!

The straight part
We know that "Thinking" is the straight/definition part of the clue. The straight part is often a synonym or definition, in this case thinking = rumination.The cryptic/wordplay part
In cryptic crossword there's often an wordplay/cryptic part as well.This part involves a more complex hint, such as an anagram, homophone, hidden word, etc.
Sadly, We don't have an explanation for this specific crossword clue yet.
What does RUMINATION mean?
RUMINATION noun- The act of ruminating; i.e. chewing cud.
- Deep thought or consideration.
- Negative cyclic thinking; persistent and recurrent worrying or brooding.
- An eating disorder characterized by repetitive regurgitation of small amounts of food from the stomach.